Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Insulinoma: diagnostic elements. 13 cases].

J Hazard, D Simon, L Perlemuter

    Presse Medicale (Paris, France : 1983)
    |October 12, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Within patient horizontal gene transfer dynamics of a bla<sub>NDM-7</sub> plasmid among four different bacterial species.

    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2025
    Same author

    [The MASK lift].

    Annales de chirurgie plastique et esthetique·2024
    Same author

    Role of the environment in transmission of Gram-negative bacteria in two consecutive outbreaks in a haematology-oncology department.

    Infection prevention in practice·2022
    Same author

    Epidemiological, clinical, and echocardiographic features, and outcome of dogs with Ebstein's anomaly: 32 cases (2002-2016).

    Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2020
    Same author

    Assessment of bovine tuberculosis surveillance effectiveness in French wildlife: An operational approach.

    Preventive veterinary medicine·2020
    Same author

    [Is AMH a fertility marker?]

    Gynecologie, obstetrique, fertilite & senologie·2019
    Same journal

    Predictive analytics and risk stratification models in internal medicine: from risk scores to real-time machine learning.

    Presse medicale (Paris, France : 1983)·2026
    Same journal

    Artificial Intelligence in skin disease therapeutics: from drug discovery to personalized treatment pathways.

    Presse medicale (Paris, France : 1983)·2026
    Same journal

    AI in clinical diagnostics in dermatology: applications, validation, and real-world use cases.

    Presse medicale (Paris, France : 1983)·2026
    Same journal

    Artificial Intelligence in medical research and publishing: progress, risks, and future perspectives.

    Presse medicale (Paris, France : 1983)·2026
    Same journal

    Ethical, legal, and regulatory challenges in AI-based healthcare tools.

    Presse medicale (Paris, France : 1983)·2026
    Same journal

    Decision-making for clinicians.

    Presse medicale (Paris, France : 1983)·2026
    See all related articles

    This study on 13 patients found that insulinomas, tumors causing inappropriate insulin secretion, often present with neurological and behavioral symptoms. Diagnosis can be delayed, but imaging techniques like phlebography aid in locating these tumors before surgery.

    Area of Science:

    • Endocrinology
    • Oncology
    • Neurosurgery

    Background:

    • Insulinomas are rare pancreatic neuroendocrine tumors responsible for endogenous hyperinsulinism.
    • Diagnosis can be challenging due to nonspecific symptoms and delayed presentation.

    Observation:

    • The study analyzed 13 patients (mean age 50.5 years) presenting with diverse symptoms including malaise, behavioral changes, coma, syncope, and hemiparesis.
    • Symptoms often occurred in the morning or between meals, indicative of hypoglycemia.
    • Diagnostic delay averaged 20.3 months, with confirmed hypoglycemia in 11/13 patients.

    Findings:

    • Inappropriate insulin secretion was confirmed through fasting tests and insulin/glucose ratio calculations.
    • Preoperative localization of insulinomas utilized various imaging modalities, with phlebography and catheterization proving most effective (8/9 cases).

    Related Experiment Videos

  • Histological examination confirmed adenoma in 12 cases, with no evidence of malignancy.

    • Implications:

    • Early recognition of characteristic hypoglycemic symptoms is crucial for timely insulinoma diagnosis.
    • Advanced imaging and biochemical tests are vital for accurate preoperative localization and surgical planning.
    • Surgical resection is the primary treatment for benign insulinomas, leading to favorable outcomes.