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Updated: Feb 7, 2026

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
Neonatal and Long-Term Consequences of Fetal Growth Restriction
Marina Colella1, Alice Frérot1, Aline Rideau Batista Novais1
1University Paris Diderot, Sorbone Paris-Cite, Inserm U1141, Neonatal intensive care unit, Assistance Publique- Hopitaux de Paris, Robert Debre Children's hospital, Paris, France.
Insights
Fetal Growth Restriction (FGR) impacts infant development, leading to long-term respiratory, cardiovascular, and neurological issues. Understanding FGR is crucial for improving infant health outcomes.
Area of Science:
- Obstetrics and Gynecology
- Neonatology
- Developmental Pediatrics
Background:
- Fetal Growth Restriction (FGR) is a prevalent adverse antenatal condition.
- FGR significantly contributes to preterm birth, perinatal mortality, and long-term health problems.
Purpose of the Study:
- To review the postnatal consequences of FGR.
- To emphasize the long-term effects of FGR on respiratory, cardiovascular, and neurological systems.
Main Methods:
- Literature review of current knowledge on FGR.
- Synthesis of data on postnatal sequelae of FGR.
Main Results:
- FGR has significant long-term impacts on respiratory function.
- Cardiovascular structures and functions are affected by FGR.
- Neurological development and function can be impaired by FGR.
Conclusions:
- FGR poses a global health challenge requiring further investigation.
- Improved understanding of FGR's etiology and its impact on organ development is essential.
Background:
Fetal Growth Restriction (FGR) is one of the most common noxious antenatal conditions in humans, inducing a substantial proportion of preterm delivery and leading to a significant increase in perinatal mortality, neurological handicaps and chronic diseases in adulthood. This review summarizes the current knowledge about the postnatal consequences of FGR, with a particular emphasis on the long-term consequences on respiratory, cardiovascular and neurological structures and functions.
Result And Conclusion:
FGR represents a global health challenge, and efforts are urgently needed to improve our understanding of the critical factors leading to FGR and subsequent insults to the developing organs.
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