Related Experiment Video For basosquamous carcinoma
Updated: Feb 7, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Detection of Felis catus papillomavirus type 2 within multicentric basosquamous carcinoma in a domestic cat
Ye-In Oh1,2, Doo-Sung Cheon3, Jung-Keun Lee4,5
1Haemaru Referral Animal Hospital, Seongnam-si 13590, Republic of Korea.
Abstract:
A 12-year-old neutered male domestic shorthair cat was presented with a 3-year history of multiple nonpruritic, ulcerated, plaque-like skin lesions but no other clinical signs. A systemic examination revealed mild lymphadenopathy. Histopathologic analysis of the skin lesions revealed multicentric basosquamous carcinoma (BSC). Immunohistochemical analysis, PCR, and sequencing detected Felis catus papillomavirus type 2 (FcaPV-2) within the tumors. As BSC is rare in cats, clinical behavior has not been established. To our knowledge, this is the first case report to demonstrate detection of FcaPV-2 within a BSC in a domestic cat.
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