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Updated: Feb 7, 2026

A Method for Ovarian Follicle Encapsulation and Culture in a Proteolytically Degradable 3 Dimensional System
Published on: March 15, 2011
Association Between Ovarian Volume-Related Dynamic Parameters and Outcomes of IVF
Abstract:
OBJECTIVE: To investigate the relationship between ovarian volume-related parameters and in vitro fertilization (IVF) outcomes in order to establish an accurate and reliable method of determining ovarian response or IVF outcomes. STUDY DESIGN: A total of 142 women undergoing controlled ovarian stimulation with gonadotropin-releasing hormone agonist were retrospectively analyzed. In each ovary, diameters in 2 perpendicular planes were measured and calculated by applying the formula for an ellipsoid: (D1xD2x(D1+D2/2)xπ/6). The total basal ovarian volume (BOV) was calculated as the sum of the bilateral ovarian volume. Total follicular volume (TFV) was defined as sum of bilateral follicular volume. The study subjects were grouped by TFV/BOV and by TFV/BOV/stimulation days. RESULTS: A significantly higher number of oocytes was retrieved in the participants with a higher TFV/BOV (p=0.002). The patients with higher TFV/BOV/stimulation days also demonstrated a significantly higher serum estradiol level on the hCG day and a higher number of retrieved oocytes (p=0.04 and 0.02, respectively). In a multivariate analysis, the TFV/BOV/stimulation days had a significant independent effect on the number of transferred embryos (p=0.01). CONCLUSION: Ovarian volume-related dynamic parameters play an important role in predicting ovarian response and IVF outcomes.
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