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[Postoperative herpetic encephalitis. Value of Klapper's diagnostic method].

P Saux, C Martin, M Baronetto

    Annales Francaises D'Anesthesie Et De Reanimation
    |January 1, 1985
    PubMed
    Summary

    A patient developed herpes encephalitis post-surgery, presenting with a rash and stupor. Prompt diagnosis using Klapper's index and treatment with nucleoside analogues led to a full recovery without complications.

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    Area of Science:

    • Neurology
    • Infectious Diseases
    • Virology

    Background:

    • Herpes simplex virus (HSV) encephalitis is a severe neurological condition.
    • Postoperative complications can include opportunistic infections.
    • Early diagnosis and treatment are crucial for patient outcomes.

    Observation:

    • A 51-year-old female developed a nasolabial vesicular eruption and stupor on postoperative day three.
    • The patient had recently undergone surgery for chronic pancreatitis with pseudocyst formation.
    • Anti-HSV antibodies were detected in blood and cerebrospinal fluid.

    Findings:

    • Klapper's anti-HSV antibody ratio supported the diagnosis of herpes encephalitis.
    • Treatment with nucleoside analogues resulted in rapid clinical improvement.

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  • The patient was discharged from the intensive care unit without sequelae.

    • Implications:

    • Highlights the importance of considering HSV encephalitis in intensive care unit patients with neurological symptoms.
    • Demonstrates the utility of Klapper's index in diagnosing herpes encephalitis.
    • Emphasizes the effectiveness of timely antiviral therapy in preventing long-term neurological damage.