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Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents
Published on: July 9, 2020
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Delivery of sevoflurane using a neonatal ventilator
Richard J Burstal1, Steven J Threlfo1
1Department of Anaesthesia, John Hunter Hospital, Newcastle, New South Wales, Australia.
Paediatric Anaesthesia
|July 14, 2018
Summary
This study adapted a neonatal ventilator to deliver sevoflurane anesthesia using a draw-over vaporizer. Bench testing confirmed stable anesthetic delivery, excluding high-frequency oscillation mode.
Area of Science:
- Anesthesiology
- Biomedical Engineering
- Neonatal Care
Background:
- Standard anesthetic ventilators lack precision for neonates.
- Neonatal ventilators cannot deliver volatile anesthesia.
Purpose of the Study:
- Adapt a neonatal ventilator for sevoflurane delivery.
- Incorporate a vaporizer and scavenging system.
Main Methods:
- Used a Diamedica draw-over vaporizer and custom scavenging system.
- Integrated equipment into the neonatal ventilator circuit.
- Implemented safety measures for correct insertion.
Main Results:
- Vaporizer output was linear and stable (4-8 L/min flow).
- Scavenging system was effective, not impacting ventilator function.
- High-frequency oscillation mode showed unpredictable concentrations.
Conclusions:
- Modified neonatal ventilator provides stable sevoflurane delivery.
- Avoid use in high-frequency oscillation mode due to unpredictable concentrations.
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