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Updated: Jul 28, 2026

Solid Phase Synthesis of a Functionalized Bis-Peptide Using "Safety Catch" Methodology
Published on: May 15, 2012
Catch Me If You Can
Muhammad Omar1, Ashwyna Sunassee2, Matthew Hayes3
1Avera McKennan Hospital and University Health Center, Sioux Falls, South Dakota.
Abstract:
Nocardia is a genus of anaerobic gram-positive bacteria that most commonly infect persons with compromised immunity. Pneumonia and soft tissue infections are seen most frequently; osteomyelitis is an uncommonly reported manifestation of nocardiosis. We report a case of pelvic osteomyelitis due to Nocardia asteroides in a patient with unrecognized acquired immune deficiency syndrome (AIDS) without evidence of concomitant pulmonary or skin infection.
Insights
Nocardia asteroides rarely causes pelvic osteomyelitis, especially in individuals with undiagnosed acquired immune deficiency syndrome (AIDS). This case highlights a rare presentation of nocardiosis in an immunocompromised patient.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Immunology
Background:
- Nocardia species are aerobic, gram-positive bacteria.
- Nocardiosis commonly affects immunocompromised individuals.
- Typical Nocardia infections include pneumonia and soft tissue infections.
Observation:
- A patient presented with pelvic osteomyelitis.
- The patient had unrecognized acquired immune deficiency syndrome (AIDS).
- No concurrent pulmonary or skin Nocardia infections were detected.
Findings:
- Pelvic osteomyelitis was diagnosed and attributed to Nocardia asteroides.
- This represents an uncommon manifestation of nocardiosis.
- The patient's underlying immunodeficiency was a key factor.
Implications:
- Highlights the diverse clinical presentations of Nocardia infections.
- Emphasizes the importance of considering nocardiosis in immunocompromised patients with unusual infections.
- Suggests pelvic osteomyelitis as a potential, albeit rare, manifestation of nocardiosis in AIDS patients.
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