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Evaluation of peripapillary choroidal distribution in children by enhanced depth imaging optical coherence tomography

Yi Zha1, Jinfei Zhuang1, Yixia Du2

  • 1The 2nd Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.

BMC Ophthalmology
|July 15, 2018
PubMed

Insights

This study found that peripapillary choroidal thickness (PPCT) in Chinese children varies by location, being thicker nasally and thinner inferiorly. Myopic children exhibited thinner PPCT, which negatively correlated with axial length.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Retinal Imaging

Background:

  • Peripapillary choroidal thickness (PPCT) is a key indicator of ocular health.
  • Understanding PPCT variations in children is crucial for early detection of visual impairments.
  • Chinese children aged 6-12 years were studied to assess PPCT and related factors.

Purpose of the Study:

  • To determine the peripapillary choroidal thickness (PPCT) in Chinese children aged 6 to 12 years.
  • To analyze factors correlated with PPCT in this pediatric population.
  • To compare PPCT between myopic and emmetropic children.

Main Methods:

  • Enhanced depth imaging optical coherence tomography (EDI-OCT) was used to measure PPCT.
  • 154 children (76 myopes, 78 emmetropes) aged 6-12 years with refractive errors from +0.50D to -5.50D were included.
  • PPCT and peripapillary retinal thickness (PPRT) were measured at nine distinct locations around the optic disc.

Main Results:

  • The mean global PPCT was 165.80 ± 39.86 μm, and mean global PPRT was 101.47 ± 10.74 μm.
  • PPCT was significantly thicker nasally and thinner inferiorly; PPRT showed the opposite pattern.
  • Myopic children had significantly thinner PPCT compared to emmetropic children across most measured locations.

Conclusions:

  • Peripapillary choroidal thickness exhibits directional asymmetry, being thicker nasally and thinner inferiorly.
  • Myopia in children is associated with reduced peripapillary choroidal thickness.
  • Increased axial length was negatively correlated with peripapillary choroidal thickness in this cohort.
Abstract

Keywords:
ChildrenEnhanced-depth imaging optical coherence tomographyMyopiaPeripapillary choroidal thicknessPeripapillary retinal thickness

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