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Predicting physical stability of ternary amorphous solid dispersions using specific mechanical energy in a hot melt

Masataka Hanada1, Scott V Jermain1, Xingyu Lu2

  • 1Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, The University of Texas at Austin, 2409 University Ave., A1920 Austin, TX 78712, USA.

International Journal of Pharmaceutics
|July 15, 2018
PubMed

Keywords:
Amorphous solid dispersionHot melt extrusionMesoporous silicaSolid-state NMRSpecific mechanical energy

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