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Anal Carcinoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology
Summary
The NCCN Guidelines for Anal Carcinoma recommend chemoradiation as primary treatment for anal cancer, with surgery as an option for select cases. Ongoing surveillance is crucial for potential further treatment.
Area of Science:
- Oncology
- Gastroenterology
- Radiology
Background:
- Squamous cell carcinoma of the anal canal and perianal region requires specific management strategies.
- Current treatment paradigms involve both localized and systemic therapeutic approaches.
Purpose of the Study:
- To outline the National Comprehensive Cancer Network (NCCN) Guidelines for Anal Carcinoma.
- To provide evidence-based recommendations for the management of anal cancer patients.
Main Methods:
- The guidelines synthesize current evidence and expert consensus.
- Recommendations cover diagnosis, treatment, and surveillance of anal carcinoma.
Main Results:
- Primary treatment typically involves chemoradiation.
- Complete margin-negative local excision is an alternative for specific early-stage lesions.
- Disease surveillance is essential for all patients, enabling further curative treatment if needed.
Conclusions:
- Optimal patient care necessitates a multidisciplinary team approach.
- Key specialties include gastroenterology, medical oncology, surgical oncology, radiation oncology, and radiology.
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