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Published on: April 19, 2024
Developmental dysplasia of the hip: A special pathology
Jun Chen1, Wen-Bing Zhang1, Jin-Zhou He1
1Department of Orthopedic, Chongqing Children's Hospital, Chongqing Medical University, Chongqing, 400014, China.
Insights
This study reports a rare case of developmental dysplasia of the hip (DDH) with a unique intra-articular osteocartilaginous tissue. This finding suggests a previously unrecognized pathology in DDH, potentially linked to femoral head fracture.
Area of Science:
- Orthopedics and Sports Medicine
- Pediatric Pathology
- Developmental Biology
Background:
- Developmental dysplasia of the hip (DDH) is a common congenital disorder with varied presentations.
- Existing research on DDH has not fully characterized all pathological variations.
- Understanding rare pathologies is crucial for comprehensive DDH management.
Observation:
- A rare case of DDH in a young child presented with a unique half-free intra-articular osteocartilaginous tissue in the hip joint.
- Advanced imaging, including MRI, was utilized to delineate the pathological changes.
- Surgical intervention allowed for gross anatomical and histopathological examination of the tissue.
Findings:
- Gross anatomy revealed the tissue perfectly matched a fossa on the femoral head.
- Histopathology showed the tissue comprised collagenous fiber and cartilage-like material.
- Immunohistochemistry confirmed type I collagen expression, indicating the tissue originated from torn articular cartilage, possibly due to a prior femoral head fracture.
Implications:
- This case highlights a potentially new pathological entity within DDH.
- The findings suggest that intra-articular osteocartilaginous tissue should be considered in the spectrum of DDH pathologies.
- Further research is warranted to understand the etiology and clinical significance of this rare finding in DDH.
Abstract:
Developmental dysplasia of the hip (DDH) is one of the most common congenital disorders in childhood. Its diverse pathological changes require different treatments and result in different outcomes. Although many studies have been conducted on DDH, some special pathology is still unrecognized. We here presented a rare case of a one-year and eleven-month old girl with DDH; a half-free intra-articular osteocartilaginous tissue was found in her right hip joint. X-ray, computer assisted tomography (CT) and magnetic resonance imaging (MRI) were performed to evaluate the pathological changes. MRI revealed some positive findings. The patient experienced open reduction and histopathological examination of the small tissue. Through gross anatomy it is a half-free intra-articular osteocartilaginous tissue, which can fully match a fossa observed at the femoral head. Histopathological examination found that the tissue was composed of collagenous fiber and cartilage-like tissue. Interestingly, we found the expression of type I collagen according to immunohistochemical analysis, which indicated that the cartilage-like tissue was formed due to laceration of the articular cartilage. This kind of disorder should be included as one of the pathologies of DDH. The most possible origin of this tissue is the femoral head which we speculate may have been fractured before.
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