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Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

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Abnormal admission kidney function predicts higher mortality in stroke patients.

Mohammad A Mekhlafi¹, Bashair M Ibrahim, Lama A Rayyis

¹Department of Neurology, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

Neurosciences (Riyadh, Saudi Arabia)

|July 16, 2018

Summary

Abnormal kidney function significantly increases the risk of death one year after stroke. Older, hypertensive men with stroke are particularly vulnerable and require targeted monitoring and early intervention.

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Area of Science:

Nephrology
Neurology
Public Health

Background:

Kidney function is crucial for overall health and can impact various medical outcomes.
Stroke is a leading cause of death and disability worldwide.
The relationship between impaired kidney function and stroke prognosis requires further investigation.

Purpose of the Study:

To examine the association between abnormal kidney function and stroke outcomes.
To identify specific risk factors and patient groups affected by impaired renal function post-stroke.

Main Methods:

Retrospective cohort study of 548 stroke patients (2010-2014) at King Abdulaziz University Hospital.
Assessed kidney function using serum creatinine and estimated glomerular filtration rate (eGFR).
Defined abnormal kidney function as Creatinine >126 mg/dl or eGFR <60 mL/min/1.73m²; proteinuria defined as urine protein dipstick >/=+1.

Main Results:

193 patients (38%) had abnormal kidney function, tending to be older, male, and hypertensive.
Abnormal kidney function was a significant predictor of one-year mortality post-stroke (adjusted OR=2.5, p=0.003).
Proteinuria alone was not associated with increased mortality.

Conclusions:

Impaired kidney function nearly doubles the risk of one-year mortality in stroke patients.
Older hypertensive men with stroke are a high-risk group requiring aggressive monitoring.
Early intervention for risk factors in vulnerable populations may improve stroke outcomes.