Related Experiment Video

Updated: Feb 7, 2026

Three-dimensional Quantification of Dendritic Spines from Pyramidal Neurons Derived from Human Induced Pluripotent Stem Cells
10:18

Three-dimensional Quantification of Dendritic Spines from Pyramidal Neurons Derived from Human Induced Pluripotent Stem Cells

Published on: October 10, 2015

13.3K

Human Cortical Pyramidal Neurons: From Spines to Spikes via Models

Guy Eyal1, Matthijs B Verhoog2,3, Guilherme Testa-Silva2

  • 1Department of Neurobiology, Hebrew University of Jerusalem, Jerusalem, Israel.

Frontiers in Cellular Neuroscience
|July 17, 2018
PubMed
Summary

This study models human neocortical pyramidal cells, revealing enhanced computational power due to unique synaptic and dendritic properties. These detailed models offer new insights into human neuron signal processing and capabilities.

Keywords:
compartmental modelingcortical excitatory synapsesdendritic spineshuman pyramidal cellsmulti objective optimizationneuron computationnon-linear dendrites

More Related Videos

Ballistic Labeling of Pyramidal Neurons in Brain Slices and in Primary Cell Culture09:40

Ballistic Labeling of Pyramidal Neurons in Brain Slices and in Primary Cell Culture

Published on: April 2, 2020

7.5K
Analysis of Dendritic Spine Morphology in Cultured CNS Neurons11:48

Analysis of Dendritic Spine Morphology in Cultured CNS Neurons

Published on: July 13, 2011

35.8K

Related Concept Videos

Biodiversity and Human Values01:24

Biodiversity and Human Values

Human civilization relies on biodiversity in many ways. Sudden changes in species biodiversity result in environmental changes that can modify weather patterns and therefore human civilizations.
17.1K
Neurons: The Axon01:21

Neurons: The Axon

Axons are long, cytoplasmic processes of nerve cells capable of propagating electrical impulses known as action potentials. The cytoplasm or axoplasm of an axon contains neurofibrils, neurotubules, small vesicles, lysosomes, mitochondria, and various enzymes, all encased within the axolemma, the plasma membrane of the axon.
The axon attaches to the cell body at a cone-shaped elevation called the axon hillock. The initial part of the axon, closest to the hillock, is known as the initial segment....
7.4K
Neuron Structure01:31

Neuron Structure

Overview
231.8K
Neuron Structure01:30

Neuron Structure

Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
18.4K
Neuronal Communication01:28

Neuronal Communication

Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
3.5K
Adrenergic Neurons: Neurotransmission01:27

Adrenergic Neurons: Neurotransmission

Postganglionic sympathetic fibers (except those supplying the sweat glands) releasing noradrenaline or norepinephrine are called noradrenergic or adrenergic neurons. Noradrenaline, dopamine, adrenaline, or epinephrine are collectively called "catecholamines" as they contain a catechol moiety and an amine side chain. The five stages of neurotransmitter release involve their synthesis, storage, release, reuptake and metabolism.
Synthesis: Catecholamine synthesis requires tyrosine, which...
5.4K