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Updated: Feb 7, 2026

Deep Brain Stimulation with Simultaneous fMRI in Rodents
Published on: February 15, 2014
Pallidal deep brain stimulation and intraoperative neurophysiology for treatment of poststroke hemiballism
Adolfo Ramirez-Zamora1, Robert S Eisinger1, Sameah A Haider2
1Department of Neurology Center for Movement Disorders and Neurorestoration Fixel Center for neurological disorders at the University of Florida Gainesville Florida.
Abstract:
Deep brain stimulation is a recognized and effective treatment for several movement disorders. Nevertheless, the efficacy of this intervention on abnormal movements secondary to structural brain pathologies is less consistent. In this report, we describe a case of hemiballism-hemichorea due to a peripartum ischemic stroke-treated with deep brain stimulation of the globus pallidus internus. Patient observed marked improvement in her symptoms at long-term follow-up. Neurophysiologic data revealed lower globus pallidus internus firing rates compared to other hyperkinetic disorders. Pallidal deep brain stimulation is a plausible option for medically refractory hemiballism-hemichorea and cumulative data from multiple centers may be used to fully evaluate its efficacy.
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