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Updated: Feb 7, 2026

Nanomechanics of Drug-target Interactions and Antibacterial Resistance Detection
Published on: October 25, 2013
Soybean-Macrophomina phaseolina-Specific Interactions and Identification of a Novel Source of Resistance
Sebastián Reznikov1, María A Chiesa1, Esteban M Pardo1
1First, third, fourth, sixth, seventh, ninth, and tenth authors: Instituto de Tecnología Agroindustrial del Noroeste Argentino (ITANOA), Estación Experimental Agroindustrial Obispo Colombres (EEAOC)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Av. William Cross 3150, C.P. T4101XAC Las Talitas, Tucumán, Argentina; second and eighth authors: Laboratorio de Fisiología Vegetal, Instituto de Investigaciones en Ciencias Agrarias de Rosario (IICAR), Universidad Nacional de Rosario (UNR) -CONICET, Parque Villarino S/N, 2125 Zavalla, Santa Fe, Argentina; and fifth author: Instituto Paraguayo de Tecnología Agraria (IPTA), Centro de Investigación Capitán Miranda, Ruta VI, Km 16, C.P. 6990 Capitán Miranda, Itapúa, Paraguay.
Abstract:
Charcoal rot, caused by the fungus Macrophomina phaseolina, is an economically important disease of soybean (Glycine max) worldwide. Objectives of the present research were to (i) study the genetic and pathogenic diversity in a collection of M. phaseolina isolates from Argentina and Paraguay and (ii) develop an improved in vitro phenotyping method to evaluate disease response of soybean genotypes to M. phaseolina isolates. Cluster analysis showed no clear association among simple sequence repeat profiles, year of collection, pathogenicity, and geographical origin of the isolates from Argentina and Paraguay. Subsequently, the response of four soybean genotypes against seven M. phaseolina isolates was evaluated in the field and the results were confirmed using the in vitro assay developed. This assay, which is based on root disease development on soybean seedlings, allowed the detection of a differential level of aggressiveness among the isolates on four soybean genotypes. The results suggest the existence of specific interactions among soybean genotypes and M. phaseolina isolates. In addition, cultivar Munasqa RR showed a superior response against M. phaseolina compared with DT 97-4290 (moderately resistant), thus becoming a novel source of resistance to charcoal rot.
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