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Updated: Feb 7, 2026

Author Spotlight: Scalable Drug Screening Protocol for Efficient Discovery of M. abscessus Treatments
Published on: October 25, 2024
How soon will digital endpoints become a cornerstone for future drug development?
Philip Boehme1, Arne Hansen2, Ronenn Roubenoff3
1Bayer Pharma AG, Cardiovascular Research, Wuppertal, Germany; Witten/Herdecke University, School of Medicine, Faculty of Health, Witten, Germany.
Abstract:
Digital technologies are transforming healthcare and will provide the basis for more patient-centric innovation in the pharmaceutical industry. Digital endpoints in clinical studies have the potential to drive innovation and reduce costly late-stage failures. This is also currently under consideration by regulatory agencies, such as the US Food and Drug Administration (FDA). The academic-industrial collaboration MOBILISED-D aims to implement and validate real-world walking speed (RWS) as a digital endpoint accepted by regulatory authorities as a first of its class. Previous work has shown that loss of mobility driven by chronic illness and frailty in older patients can be a relevant readout or effect of different diseases and various organ systems.
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