The assessment of platelet function using multiple electrode aggregometry in practical procedures in anaesthesia.

Area of Science:

• Hematology
• Clinical Pathology

Background:

• Platelets are critical for primary hemostasis.
• Prompt assessment of platelet function is vital for patients undergoing emergency surgery.
• This article details experience with whole-blood multiple electrode aggregometry (MEA) for platelet function assessment.

Observation:

• A retrospective analysis of three patients with thrombocytopathy and normal platelet counts was conducted.
• Standard laboratory tests and MEA were used for platelet function assessment.
• Two cases involved platelet dysfunction due to antiplatelet drugs; one was linked to chronic kidney disease.

Findings:

• Multiple electrode aggregometry (MEA) demonstrated utility in diagnosing platelet dysfunction.
• MEA identified antiplatelet drug effects and chronic kidney disease as causes of thrombocytopathy.
• The study highlights MEA's role in complex clinical scenarios.

Implications:

• Platelet function assessment is crucial for patients with suspected hemostatic disturbances.
• MEA supports clinical decision-making in perioperative settings, especially for high-risk patients.
• Enhanced perioperative safety can be achieved through accurate platelet function testing.