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Rheological behaviour of selected commercially available baby formulas in simulated human digestive system
Sangeeta Prakash1, Qian Ma1, Bhesh Bhandari1
1School of Agriculture and Food Sciences, The University of Queensland, 4072, Australia.
Insights
Infant formulas
Area of Science:
- Food Science
- Rheology
- Pediatric Nutrition
Background:
- Infant formulas are crucial for infants (<12 months) lacking mother's milk.
- Understanding formula rheology aids in optimizing infant nutrition and health.
- Gastroesophageal reflux is a common concern in infants.
Purpose of the Study:
- To investigate the rheological properties of four infant formulas during simulated digestion.
- To compare the viscosity changes of different infant formulas in vitro.
- To explore the potential role of formula viscosity in preventing gastroesophageal reflux.
Main Methods:
- Simulated in vitro digestion model.
- Rheological measurements (viscosity) at 15-minute intervals.
- Analysis of four commercial infant formulas: newborn, anti-reflux, soy, and lactose-free.
Main Results:
- Saliva's enzymatic action did not significantly alter formula viscosity due to short oral residence time.
- Formula viscosity decreased over time during simulated gastrointestinal digestion.
- Anti-reflux formula exhibited consistently higher viscosity compared to other formulas.
Conclusions:
- Infant formula viscosity changes during digestion.
- Higher viscosity in anti-reflux formulas may contribute to reducing gastroesophageal reflux.
- Further research into infant formula rheology can inform product development for improved infant health outcomes.
Abstract:
A variety of formulas are available in the global market for infants (<12months old) who do not have access to mother's milk. The rheological properties of four different commercially available infant formulas - newborn, anti-reflux, soy and lactose free - in an in vitro digestive system were investigated. The enzymatic saliva when mixed with the formulas did not influence their viscosity in the mouth possibly due to the short residence time. Systematic measurement (every 15min) of viscosity during gastrointestinal digestion process revealed a decrease in viscosity as time progressed. The most interesting observation was that the viscosity of the anti-reflux formula was relatively higher compared to the other formulas throughout the simulated gastrointestinal digestion process. The results suggest that viscosity of the infant formula in the stomach may have a role to play in preventing gastroesophageal reflux.
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