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Updated: Feb 7, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy:
Michael A Borger1, Paul W M Fedak2, Elizabeth H Stephens3
1Leipzig Heart Center, Cardiac Surgery, University of Leipzig, Leipzig, Germany.
Insights
Bicuspid aortic valve disease, affecting 1-2% of the population, often involves thoracic aortic dilation. These guidelines summarize management strategies for this complex cardiac condition.
Area of Science:
- Cardiology
- Genetics
- Vascular Biology
Background:
- Bicuspid aortic valve disease is a prevalent congenital heart defect.
- Associated aortopathy, including thoracic aortic dilation, affects approximately 40% of patients.
- Existing guidelines offer limited focus on bicuspid aortic valve-related aortopathy management.
Purpose of the Study:
- To provide an executive summary of the American Association for Thoracic Surgery Guidelines on Bicuspid Aortic Valve-Related Aortopathy.
- To offer clinicians a comprehensive review of this specific disease process.
- To guide the daily management of patients with bicuspid aortic valve aortopathy.
Main Methods:
- This document is an executive summary of comprehensive clinical guidelines.
- It synthesizes information on natural history, pathology, imaging, and surgical indications.
- Recommendations for surveillance, follow-up, and future research are included.
Main Results:
- The guidelines cover key aspects of bicuspid aortic valve aortopathy.
- This summary condenses essential information for clinical practice.
- It addresses the natural history, phenotypic expression, and molecular mechanisms.
Conclusions:
- This executive summary provides a current and comprehensive review of bicuspid aortic valve aortopathy.
- It aims to guide clinicians in managing patients with this condition.
- The guidelines emphasize the importance of a focused approach to bicuspid aortic valve-related aortopathy.
Abstract:
Bicuspid aortic valve disease is a common congenital cardiac disorder, being present in 1% to 2% of the general population. Associated aortopathy is a common finding in patients with bicuspid aortic valve disease, with thoracic aortic dilation noted in approximately 40% of patients in referral centers. Several previous consensus statements and guidelines have addressed the management of bicuspid aortic valve-associated aortopathy, but none focused entirely on this disease process. The current document is an executive summary of "The American Association for Thoracic Surgery Guidelines on Bicuspid Aortic Valve-Related Aortopathy." All major aspects of bicuspid aortic valve aortopathy, including natural history, phenotypic expression, histology and molecular pathomechanisms, imaging, indications for surgery, surveillance, and follow-up, and recommendations for future research are contained within these guidelines. The current executive summary serves as a condensed version of the guidelines to provide clinicians with a current and comprehensive review of bicuspid aortic valve aortopathy and to guide the daily management of these complex patients.
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