Related Experiment Video
Updated: Feb 7, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Transcatheter Closure of a Huge Ductus Arteriosus in a Severely Ill Neonate
Seigo Okada1, Jun Muneuchi1, Yusaku Nagatomo1
1Department of Pediatrics, Japan Community Healthcare Organization, Kyushu Hospital.
Abstract:
Hemodynamically significant patent ductus arteriosus (PDA) in preterm infants increases morbidity and mortality. Here we describe a 12-day-old neonate with a huge PDA who developed pulmonary hemorrhage following disseminated intravascular clotting and multiple organ failure. Medical treatment or surgical ligation could not be performed because of the patient's poor condition. Transcatheter closure using a commercially available device (Amplatzer Vascular Plug II) successfully treated the huge PDA without major complications. The Amplatzer Vascular Plug II approach might become a new option for PDA closure in small infants, including those who are critically ill.
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