Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Causality in Epidemiology01:21

Causality in Epidemiology

1.7K
Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
1.7K
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

425
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
425
Drug Discovery: Overview01:26

Drug Discovery: Overview

11.8K
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
11.8K
Criteria for Causality: Bradford Hill Criteria - II01:28

Criteria for Causality: Bradford Hill Criteria - II

1.3K
The Bradford Hill criteria serve as guidelines for establishing causative links in epidemiological research. Beyond Strength, Consistency, Specificity, and Temporality, key criteria also include Biological Gradient, Plausibility, Coherence, Experiment, and Analogy. These principles assist scientists in assessing the likelihood of causation in complex biological contexts. Below is a summary of these concepts:
1.3K
Criteria for Causality: Bradford Hill Criteria - I01:30

Criteria for Causality: Bradford Hill Criteria - I

1.1K
The Bradford Hill criteria are a group of principles that provide a framework to determine a causal relationship between a specific factor and a disease. There are nine criteria that are pivotal in assessing causality in epidemiological studies. Here's a closer look at Strength, Consistency, Specificity, and Temporality criteria with definitions and examples:
1.1K
Optimal Foraging00:48

Optimal Foraging

13.9K
How animals obtain and eat their food is called foraging behavior. Foraging can include searching for plants and hunting for prey and depends on the species and environment.
13.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diminished rest-activity rhythm is associated with postoperative complications and mortality: A prospective cohort study of UK Biobank participants.

European journal of anaesthesiology·2026
Same author

Corrigendum to "Injectable hydrogel for postoperative synergistic photothermal-chemodynamic tumor and anti-infection therapy" [Biomaterials 280(2022) 121289].

Biomaterials·2026
Same author

Post-Pandemic Influenza Resurgence in Guangzhou, China: Impact of COVID-19 Interventions and Immune Alterations.

Journal of medical virology·2026
Same author

Detection of Artemisia mongolica floss adulteration in moxa floss: A strategy based on UPLC-Q/Orbitrap HRMS, chromatographic analysis, and machine learning.

Journal of pharmaceutical and biomedical analysis·2026
Same author

Data-driven differentiation analysis of urban high-tech industries: Research on bibliometrics and large language models.

PloS one·2026
Same author

Contrastive diffusion model for exploring mathematical expressions from data.

Neural networks : the official journal of the International Neural Network Society·2026
Same journal

Correction: Chen et al. Chemical Composition of <i>Litsea pungens</i> Essential Oil and Its Potential Antioxidant and Antimicrobial Activities. <i>Molecules</i> 2023, <i>28</i>, 6835.

Molecules (Basel, Switzerland)·2026
Same journal

Correction: Ruan et al. Comparison of Extraction, Isolation, Purification, Structural Characterization and Immunomodulatory Activity of Polysaccharides from Two Species of <i>Cistanche</i>. <i>Molecules</i> 2025, <i>30</i>, 4754.

Molecules (Basel, Switzerland)·2026
Same journal

Correction: Li et al. Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway. <i>Molecules</i> 2022, <i>27</i>, 6311.

Molecules (Basel, Switzerland)·2026
Same journal

Correction: Zueva et al. Steady-State Kinetics of Enzyme-Catalyzed Hydrolysis of Echothiophate, a P-S Bonded Organophosphorus as Monitored by Spectrofluorimetry. <i>Molecules</i> 2020, <i>25</i>, 1371.

Molecules (Basel, Switzerland)·2026
Same journal

1,4-Diazatriphenylene and Its Hetero-Fused Analogs: Synthesis and Applications.

Molecules (Basel, Switzerland)·2026
Same journal

Comparative Phytochemical Studies on the Aerial Parts of <i>Teucrium davaeanum</i> Coss. and <i>Teucrium zanonii</i> Pamp.

Molecules (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: Feb 7, 2026

Test Samples for Optimizing STORM Super-Resolution Microscopy
16:52

Test Samples for Optimizing STORM Super-Resolution Microscopy

Published on: September 6, 2013

31.6K

Causal Discovery Combining K2 with Brain Storm Optimization Algorithm.

Yinghan Hong1,2, Zhifeng Hao3,4, Guizhen Mai5

  • 1School of Computer Science and Technology, Guangdong University of Technology, Guangzhou 510006, China. honyinghan@163.com.

Molecules (Basel, Switzerland)
|July 18, 2018
PubMed
Summary
This summary is machine-generated.

This study introduces K2-BSO, an improved causal discovery algorithm. It efficiently identifies causal relationships in large datasets by optimizing node order, outperforming existing methods.

Keywords:
Bayesian causal modelK2brain storm optimizationcausal direction learning

More Related Videos

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course
11:33

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course

Published on: July 18, 2014

44.0K
Spatial Multiobjective Optimization of Agricultural Conservation Practices using a SWAT Model and an Evolutionary Algorithm
11:53

Spatial Multiobjective Optimization of Agricultural Conservation Practices using a SWAT Model and an Evolutionary Algorithm

Published on: December 9, 2012

13.5K

Related Experiment Videos

Last Updated: Feb 7, 2026

Test Samples for Optimizing STORM Super-Resolution Microscopy
16:52

Test Samples for Optimizing STORM Super-Resolution Microscopy

Published on: September 6, 2013

31.6K
Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course
11:33

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course

Published on: July 18, 2014

44.0K
Spatial Multiobjective Optimization of Agricultural Conservation Practices using a SWAT Model and an Evolutionary Algorithm
11:53

Spatial Multiobjective Optimization of Agricultural Conservation Practices using a SWAT Model and an Evolutionary Algorithm

Published on: December 9, 2012

13.5K

Area of Science:

  • Causal inference
  • Machine learning
  • Data science

Background:

  • Causal discovery is crucial for scientific discovery and data science.
  • Constraint-based causal discovery methods struggle with large, complex datasets.
  • Existing methods often fail to scale effectively for large-scale causal structure learning.

Purpose of the Study:

  • To develop an improved causal structure learning algorithm for large datasets.
  • To enhance the efficiency and scalability of causal discovery methods.
  • To address limitations of traditional constraint-based approaches in complex scenarios.

Main Methods:

  • Introduced Brain Storm Optimization (BSO) for searching optimal topological node orders.
  • Combined K2 algorithm with BSO, creating the K2-BSO algorithm.
  • Designed a novel distance function for BSO's clustering step, tailored to K2's mechanism.

Main Results:

  • K2-BSO significantly reduces the search space from graph space to topological order space.
  • The method demonstrated superior performance compared to traditional search and score methods.
  • Experimental results on real-world datasets confirmed K2-BSO's effectiveness over genetic algorithm-based methods.

Conclusions:

  • K2-BSO offers a scalable and efficient solution for causal discovery in large datasets.
  • The algorithm successfully overcomes the limitations of traditional constraint-based methods.
  • This approach holds significant promise for advancing causal inference in complex systems.