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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Preschool-onset obsessive-compulsive disorder with complete remission
Dai Miyawaki1, Ayako Goto1, Yoshihiro Iwakura1,2
1Department of Neuropsychiatry, Osaka City University Graduate School of Medicine, Osaka, Japan, miyawaki@med.osaka-cu.ac.jp.
This case report details the successful treatment and long-term remission of severe early-onset obsessive-compulsive disorder (OCD) in a preschooler. Family-based cognitive-behavioral therapy (CBT) and medication led to a complete cure, offering hope for similar cases.
Area of Science:
- Child and Adolescent Psychiatry
- Neuroscience
- Psychology
Background:
- Early-onset obsessive-compulsive disorder (OCD) is often more severe and less responsive to treatment than later-onset forms.
- Complete remission in preschool-onset OCD, particularly severe cases, is rarely reported.
- Preschool-onset OCD may be misdiagnosed as separation anxiety disorder, delaying appropriate intervention.
Observation:
- A 6-year-old girl presented with severe OCD symptoms starting at age 3, including contamination fears, excessive washing, checking rituals, and refusal to eat or dress.
- Initial inpatient pediatric treatment yielded no improvement.
- The patient was transferred for specialized psychiatric care.
Findings:
- Successful treatment was achieved through family-based cognitive-behavioral therapy (CBT) combined with a short-term, low-dose course of fluvoxamine in an inpatient setting.
- The patient experienced complete remission of OCD symptoms for over 3 years.
- At age 9, she exhibits good global functioning and no longer requires treatment.
Implications:
- This case demonstrates that severe preschool-onset OCD can achieve long-term remission with intensive, family-based inpatient treatment.
- Family-based CBT is a viable and effective treatment for hospitalized preschoolers with severe OCD.
- Early detection and intervention are crucial for improving remission rates in very young children with OCD.
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