Changes in Uterine Cancer Incidence Rates in Egypt.

Area of Science:

• Gynecologic Oncology
• Epidemiology
• Public Health

Background:

• Uterine cancer incidence varies globally, with higher rates in developed nations.
• Egypt exhibits lower uterine cancer rates compared to Middle Eastern averages.
• This study investigates uterine cancer incidence and patient profiles in Egypt's Gharbiah province.

Purpose of the Study:

• To determine the incidence rate of uterine cancer in Gharbiah province, Egypt.
• To characterize the demographic and clinical features of uterine cancer patients in the region.
• To analyze trends in uterine cancer incidence over a 12-year period.

Main Methods:

• Utilized data from 660 uterine cancer patients diagnosed between 1999 and 2010.
• Extracted information from the Gharbiah Cancer Registry, Egypt's sole population-based registry.
• Calculated crude rates, age-standardized rates (ASR), and age-specific rates, correlating them with patient demographics and clinical data.

Main Results:

• Confirmed a low age-standardized rate (ASR) of uterine cancer in Egypt (4.1 per 100,000).
• Observed a significant increase in incidence rates over the 12-year study period.
• Found that most patients were postmenopausal, diagnosed at early stages, had adenocarcinoma, and resided in urban areas.

Conclusions:

• The study confirms a low but increasing incidence of uterine cancer in Egypt's Gharbiah province.
• Further research is recommended to explore the impact of hysterectomy, rural-urban rate variations, and nutritional transitions on incidence.
• Understanding these factors is crucial for public health strategies and targeted interventions.