Analysis of risk factors for stage I lung adenocarcinoma using low-dose high-resolution computed tomography

Risk factors for stage I lung adenocarcinoma were analyzed using low-dose high-resolution computed tomography (CT). The patients were divided into case group (stage I lung adenocarcinoma patients) and control group (benign pulmonary nodules patients). All patients were subjected to low-dose high-resolution CT. Multiple linear regression was performed to analyze the CT imaging features of the two groups. Stage I lung adenocarcinoma patients were significantly associated with nodular site (X₃, upper left lobe) [95% CI (1.796, 54.695), p=0.008], nodule type (X₄) (p<0.001), nodule size (X₅) [95% CI (0.614, 0.803), p<0.001], spicule sign (X₇) [95% CI (0.029, 0.580), p=0.008], lobulation sign (X₈) [95% CI (0.048, 0.673), p=0.011]. The stepwise regression equation is: Logistic (p) =-12.009 + 2.294X₃ - 0.327X₄ - 0.354X₅ - 2.042X₇ - 1.713X₈. Risk factors of low-dose and high-resolution CT imaging for patients with stage I lung adenocarcinoma are nodular site (upper left lobe), nodule type, nodule size, spicule sign, and lobulation sign.