Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

First Law: Particles in One-dimensional Equilibrium01:10

First Law: Particles in One-dimensional Equilibrium

8.2K
Newton's first law of motion states that a body at rest remains at rest, or if in motion, remains in motion at constant velocity, unless acted on by a net external force. It also states that there must be a cause for any change in velocity (a change in either magnitude or direction) to occur. This cause is a net external force. For example, consider what happens to an object sliding along a rough horizontal surface. The object quickly grinds to a halt, due to the net force of friction. If...
8.2K
First Law: Particles in Two-dimensional Equilibrium01:18

First Law: Particles in Two-dimensional Equilibrium

16.8K
Recall that a particle in equilibrium is one for which the external forces are balanced. Static equilibrium involves objects at rest, and dynamic equilibrium involves objects in motion without acceleration; but it is important to remember that these conditions are relative. For instance, an object may be at rest when viewed from one frame of reference, but that same object would appear to be in motion when viewed by someone moving at a constant velocity.
Newton's first law tells us about...
16.8K
Binary Fission01:26

Binary Fission

3.2K
Binary fission is the primary mode of asexual reproduction in prokaryotes, such as bacteria. It results in the production of two genetically identical daughter cells. This highly efficient process ensures the rapid propagation of bacterial populations under favorable conditions and involves coordinated cellular and molecular events.DNA Replication and SeparationThe process begins with the replication of the bacterial chromosome. The circular DNA molecule unwinds at a specific origin of...
3.2K
Binary Fission01:20

Binary Fission

63.8K
Fission is the division of a single entity into two or more parts, which regenerate into separate entities that resemble the original. Organisms in the Archaea and Bacteria domains reproduce using binary fission, in which a parent cell splits into two parts that can each grow to the size of the original parent cell. This asexual method of reproduction produces cells that are all genetically identical.
63.8K
Protein Complex Assembly02:41

Protein Complex Assembly

16.8K
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
16.8K
The Nucleosome Core Particle02:10

The Nucleosome Core Particle

14.5K
Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins.
The paradox
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...
14.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Indole-Derived Compounds as Redox-Modulators: Antioxidant Mechanisms in Neuronal Protection.

Molecules (Basel, Switzerland)·2026
Same author

Active Oxygenated Group-Rich Polymer Electrolyte Synchronizing Bilateral Interfacial Stabilization and Accelerated Kinetics for High-Performance Solid-State Li-O<sub>2</sub> Batteries.

Angewandte Chemie (International ed. in English)·2026
Same author

Role of Microbial Toxins in Neurodegenerative Diseases: Insights and Future Perspectives.

Biomolecules·2026
Same author

Erratum: "Anisotropic coarse-grain Monte Carlo simulations of lysozyme, lactoferrin, and NISTmAb by precomputing atomistic models" [J. Chem. Phys. 161, 094113 (2024)].

The Journal of chemical physics·2026
Same author

Biomolecular Condensates Act as Distinct Solvation Environments That Reshape Amino Acid p<i>K</i><sub>a</sub> Values.

Journal of the American Chemical Society·2026
Same author

Learning molecular determinants of selective small-molecule partitioning across biomolecular condensates.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: Feb 7, 2026

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles
12:33

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Published on: February 4, 2013

22.2K

Assembly of three-dimensional binary superlattices from multi-flavored particles.

Evan Pretti1, Hasan Zerze, Minseok Song

  • 1Lehigh University, Chemical and Biomolecular Engineering, 111 Research Dr., Bethlehem, Pennsylvania 18015-4791, USA. jeetain@lehigh.edu.

Soft Matter
|July 18, 2018
PubMed
Summary

Multi-flavoring DNA nanoparticles enable enthalpic control over binary superlattice self-assembly. By tuning like-particle interactions, researchers can dictate crystal formation and composition for advanced materials design.

More Related Videos

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
09:47

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes

Published on: February 19, 2016

10.1K
Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages
08:46

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Published on: April 13, 2016

10.5K

Related Experiment Videos

Last Updated: Feb 7, 2026

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles
12:33

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Published on: February 4, 2013

22.2K
Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
09:47

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes

Published on: February 19, 2016

10.1K
Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages
08:46

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Published on: April 13, 2016

10.5K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biophysics

Background:

  • Colloidal particle self-assembly is key for advanced materials.
  • DNA-mediated assembly traditionally relies on pairwise interactions and size asymmetry.
  • The multi-flavoring motif allows independent control over all pairwise interactions.

Purpose of the Study:

  • To investigate the self-assembly of multi-flavored binary colloidal systems.
  • To demonstrate enthalpic control over crystal formation by tuning interactions.
  • To explore the generation of compositionally ordered crystals.

Main Methods:

  • Implicit modeling of micron-sized DNA-functionalized particles using Fermi-Jagla interactions.
  • Molecular dynamics simulations.
  • Wang-Landau Monte Carlo simulations.

Main Results:

  • Self-assembly can be controlled purely enthalpically by tuning like-particle interactions.
  • Various crystal morphologies were assembled by adjusting interaction strengths.
  • Pure, compositionally ordered crystals were generated through careful interaction selection.
  • Crystal composition and assembled structures are sensitive to interaction strengths and solution stoichiometry.

Conclusions:

  • The multi-flavoring approach offers precise control over binary superlattice self-assembly.
  • Enthalpic control, independent of particle size, is achievable.
  • This method facilitates the design of novel ordered materials with tunable compositions.