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Updated: Feb 7, 2026

Measuring Phagocytosis of Aspergillus fumigatus Conidia by Human Leukocytes using Flow Cytometry
Published on: December 7, 2019
Hospitalized Patient as Source of Aspergillus fumigatus, 2015
Abstract:
Hospital-acquired aspergillosis is usually associated with environmental contamination. In 2015, continuous monitoring of airborne fungi and multilocus variable-number tandem-repeat analysis identified the source of Aspergillus fumigatus as the airway of a patient. Therefore, patients colonized with Aspergillus spp. should be treated in airborne infection isolation rooms.
Insights
Hospital-acquired aspergillosis can originate from patients, not just the environment. Continuous monitoring and genetic analysis identified a patient's airway as the source of Aspergillus fumigatus, necessitating isolation protocols.
Area of Science:
- Medical Mycology
- Infectious Disease Epidemiology
- Hospital Infection Control
Background:
- Hospital-acquired aspergillosis is a significant concern, often linked to environmental fungal contamination.
- Standard infection control measures primarily focus on environmental sources of Aspergillus species.
Observation:
- In 2015, continuous monitoring of airborne fungi was implemented in a healthcare setting.
- Multilocus variable-number tandem-repeat analysis (MLVA) was employed for molecular typing of Aspergillus isolates.
Findings:
- The source of Aspergillus fumigatus was traced to the airway of a colonized patient.
- This finding challenges the assumption that environmental contamination is the sole origin of hospital-acquired aspergillosis.
Implications:
- Patients colonized with Aspergillus species require specific management strategies to prevent transmission.
- Implementation of airborne infection isolation rooms for Aspergillus-colonized patients is recommended to enhance patient safety.
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Published on: September 18, 2021
11:30Quantitative Analysis of Aspergillus nidulans Growth Rate using Live Microscopy and Open-Source Software
Published on: July 24, 2021
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