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Updated: Feb 7, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
[Severe poisoning with naphazoline: update from a therapeutic error]
Mariano Díaz1, Elizabeth Granson2, Jesica Taiman2
1Centro Nacional de Intoxicaciones, Hospital Nacional Profesor Alejandro Posadas, El Palomar, Buenos Aires. marianotox@yahoo.com.ar.
Abstract:
Naphazoline is a drug commonly used as a decongestant in adult patients. Its indication in Pediatrics is not frequent, being approved its use from the age of 12 for the toxic effects it possesses. Intoxication in children generates a potentially serious clinical picture. It is characterized by the immediate appearance of hypotonia, deterioration of the sensory, hypothermia and bradycardia of variable degree of clinical compromise. Although it is an infrequent intoxication, the anamnesis and the initial management of the patient are the key in the evolution. We present a 4-year-old boy who, as a therapeutic error, receives this drug, emphasizing the rapid and potentially severe establishment of the clinical picture.
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