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A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
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Management and treatment of deep vein thrombosis in special populations

Gudula Boon1, L F Van Dam1, F A Klok1

  • 1a Department of Thrombosis and Hemostasis , Leiden University Medical Center , Leiden , The Netherlands.

Expert Review of Hematology
|July 18, 2018
PubMed

Insights

Treating venous thromboembolism (VTE), like deep vein thrombosis (DVT), presents unique challenges in special populations, including cancer patients and pregnant women, due to increased risks.

Area of Science:

  • Cardiovascular Medicine
  • Hematology

Background:

  • Venous thromboembolism (VTE), encompassing deep vein thrombosis (DVT) and pulmonary embolism (PE), is a significant cardiovascular disease.
  • DVT requires prompt treatment to prevent life-threatening complications, though special populations present unique therapeutic challenges.

Purpose of the Study:

  • To review the complexities and current treatment strategies for DVT in specific patient groups.
  • To highlight the distinct considerations for cancer-associated VTE, extensive DVT, recurrent DVT, and DVT in pregnancy.

Main Methods:

  • Review of current literature and clinical trial data concerning DVT management in special populations.
  • Analysis of treatment differences based on patient-specific factors like cancer, extent of thrombosis, recurrence, and pregnancy status.

Main Results:

  • Cancer-associated VTE requires tailored treatment due to disease interventions and elevated bleeding risks.
  • Catheter-directed thrombolysis for extensive DVT lacks a standard recommendation despite investigation.
  • Diagnosing recurrent DVT and managing DVT in pregnancy involve specific complexities and risks.

Conclusions:

  • DVT treatment in special populations is complicated by high thrombotic and bleeding risks.
  • Individualized treatment strategies are essential for managing DVT in diverse and high-risk patient groups.
Abstract

Keywords:
Deep vein thrombosiscancerextensivepregnancyrecurrence

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