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In most substances, the current flow is proportional to the voltage applied to it. A simple relationship between the values of current, voltage, and resistance is known as Ohm's law. Nonohmic devices do not exhibit a linear relationship between voltage and current. One such device is the semiconducting circuit element known as a diode. A diode is a circuit device that allows current flow in only one direction.
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Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
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Rapid Fabrication of Custom Microfluidic Devices for Research and Educational Applications
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End-to-End Sample Tracking in the Laboratory Using a Custom Internet of Things Device.

William Neil1, Greg Zipp1, Gregory Nemeth2

  • 11 Bristol-Myers Squibb, Princeton, NJ, USA.

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|July 18, 2018
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Summary

A new Internet of Things (IoT) device enables end-to-end tracking of barcoded lab containers, even during manual steps and with non-scanning instruments. This innovation improves workflow visibility in high-throughput laboratories.

Keywords:
2D barcodeInternet of ThingsRaspberry Picentrifugal evaporationsample tracking

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Area of Science:

  • Laboratory Automation
  • Analytical Chemistry
  • Biotechnology

Background:

  • High-throughput laboratories often face challenges in fully tracking barcoded sample containers through manual workflow steps.
  • Existing instrumentation may lack integrated barcode scanners, creating data gaps during sample processing and temporary storage.
  • Manual tracking methods are prone to errors and inefficiencies in complex multistep workflows.

Purpose of the Study:

  • To develop and describe a custom Internet of Things (IoT) device for comprehensive tracking of barcoded containers in a laboratory setting.
  • To address the limitations of current tracking systems, particularly during manual interventions and with non-scanning equipment.
  • To provide a scalable and accessible IoT solution for enhancing laboratory workflow management.

Main Methods:

  • A low-cost, headless IoT computer was integrated with a barcode reader and a multicolor LED strip.
  • The device was designed to read container barcodes and transmit minimal data to back-end systems.
  • Aural and visual feedback mechanisms were implemented to alert users to system responses.

Main Results:

  • The custom IoT device successfully enabled end-to-end tracking of barcoded containers throughout the laboratory workflow.
  • The system effectively captured data during manual handling and when using instruments without integrated barcode scanners.
  • Users received timely alerts via audio and visual cues upon data processing.

Conclusions:

  • The developed IoT device provides a practical solution for bridging tracking gaps in high-throughput laboratory workflows.
  • The model facilitates simple and rapid deployment of IoT technology within the broader scientific community.
  • Open-source release of code and configurations will promote widespread adoption and further development.