GIVE: portable genome browsers for personal websites

Area of Science:

• Bioinformatics
• Genomics
• Web Development

Background:

• The increasing volume and variety of genomic data necessitate adaptable and portable genome visualization tools.
• Existing genome browsers often require significant technical expertise or system administration privileges, limiting accessibility.
• There is a need for user-friendly solutions to integrate diverse genomic data types into personalized web environments.

Purpose of the Study:

• To introduce GIVE (Genomic Information Visualization Engine), an open-source programming library.
• To enable users to create personalized, interactive genome browsers easily.
• To facilitate the integration of various genomic data types into personal webpages.

Main Methods:

• GIVE is a programming library that allows users to embed interactive genomic data visualizations.
• It supports multiple data types, including genome annotation, linear quantitative data, and genome interaction data.
• The library includes HUG (HTML Universal Generator), a graphical interface for automatic HTML code generation.

Main Results:

• Users can create personalized genome browsers by inserting HTML tags into their webpages.
• The HUG interface simplifies the process by automatically generating displayable HTML code.
• Generated visualizations can be directly embedded, saved, or shared with collaborators.

Conclusions:

• GIVE provides a portable and versatile solution for personalized genome browser creation.
• It empowers users to visualize diverse genomic data interactively without requiring system administrator privileges.
• The tool enhances the accessibility and shareability of genomic data visualizations for researchers and collaborators.