Related Experiment Video
Updated: Feb 7, 2026

05:28
Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
250
Clinical validation of a pressure-standardized compression mammography system
D den Boer1, L A J Dam-Vervloet1, M F Boomsma2
1Department of Medical Physics, Isala Hospital Zwolle, The Netherlands.
European Journal of Radiology
|July 19, 2018
Summary
A new pressure-standardized compression mammography (PSCM) system significantly reduces breast compression pain and over-compression, especially for smaller breasts, compared to conventional force-standardized methods.
Area of Science:
- Radiology
- Medical Imaging
- Biomedical Engineering
Background:
- Mammography is crucial for breast cancer screening.
- Patient discomfort during mammography is a significant issue, potentially affecting screening adherence.
- Conventional force-standardized compression mammography (FSCM) can lead to variable pressure due to differing breast sizes and contact areas.
Purpose of the Study:
- To validate a pressure-standardized compression mammography (PSCM) system.
- To assess if PSCM reduces discomfort and pain by standardizing applied pressure.
- To compare PSCM with conventional FSCM in terms of applied pressure and its dependency on breast characteristics.
Main Methods:
- Retrospective analysis of 300 mammograms (150 FSCM, 150 PSCM) from 39 patients.
- Intra-individual comparison of FSCM and PSCM techniques.
- Calculation of applied pressure by dividing compression force by the contact area between the breast and the compression paddle.
Main Results:
- Mean pressure significantly decreased from 17.1 to 12.8 kPa with PSCM (p < 0.001).
- PSCM showed minimal dependency of applied pressure on breast contact area, unlike FSCM.
- The rate of over-compressions reduced from 26% to 2% with PSCM, benefiting patients with smaller breasts.
Conclusions:
- PSCM reduces average breast compression pressure compared to FSCM.
- Standardized pressure with PSCM may decrease patient discomfort and pain.
- Consistent image quality from PSCM could potentially enhance diagnostic performance.
More Related Videos
Related Concept Videos
Reliability and Validity
14.1K
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
14.1K
Vapor Pressure
40.9K
When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase molecules move randomly about, they will occasionally collide with the surface of the condensed phase, and in some cases, these collisions will result in the molecules re-entering the condensed phase. The change from the gas phase to the liquid is called condensation. When the rate of condensation becomes equal to the rate of vaporization, neither the amount of the liquid nor the amount of the vapor...
40.9K
Standard Enthalpy of Formation
49.3K
Enthalpy changes are typically tabulated for reactions in which both the reactants and products are at the same conditions. A standard state is a commonly accepted set of conditions used as a reference point for the determination of properties under other different conditions. For chemists, the IUPAC standard state refers to materials under a pressure of 1 bar and solutions at 1 M and does not specify a temperature. Many thermochemical tables list values with a standard state of 1 atm. Because...
49.3K
Data Validation
2.1K
Method validation is a crucial process in analytical chemistry designed to confirm that a given method consistently produces reliable and high-quality results. This process is essential when a method is applied to different sample matrices or when procedural modifications are made, ensuring that the results meet acceptable standards across various applications.
Key parameters for method validation include:
Key parameters for method validation include:
2.1K
Data Validation
6.8K
Data validation is an essential part of a comprehensive assessment. Validation is confirming or verifying and opening the door to gathering more assessment data as it clarifies vague or unclear data. The process of checking and verifying the collected information is called data validation. The primary purpose of data validation is to ensure data is as free from error, bias, and misinterpretation as possible.
Nursing assessment guides are generally based on holistic models rather than medical...
Nursing assessment guides are generally based on holistic models rather than medical...
6.8K
Behavior of Concrete Under Compressive Load
643
Concrete exhibits specific behaviors under different compressive loads. Understanding this is crucial for understanding its structural integrity. When concrete undergoes uniaxial compression, it tends to develop cracks that run parallel to the direction of the force. These parallel cracks stem from localized tensile stresses that occur perpendicular to the compression direction. Additionally, angled cracks may appear due to the formation of shear planes.
As the concrete specimen fractures under...
As the concrete specimen fractures under...
643

