Related Experiment Video
Updated: Feb 7, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
An overview of recent developments in FLUKA PET tools.
R S Augusto1, J Bauer2, O Bouhali3
1CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland; Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching, Germany.
New FLUKA Positron-Emission-Tomography (PET) tools offer advanced Monte Carlo simulations for medical physics and hadrontherapy verification. These tools enable detailed PET scanner modeling and data analysis for research and development.
Area of Science:
- Medical Physics
- Particle Physics
- Nuclear Medicine
Background:
- Positron-Emission-Tomography (PET) is a crucial imaging technique in nuclear medicine.
- Its application in hadrontherapy requires advanced simulation tools for verification.
- Monte Carlo (MC) simulations are essential for theoretical and experimental research in this area.
Purpose of the Study:
- To detail new developments in FLUKA Positron-Emission-Tomography (PET) simulation tools.
- To provide a comprehensive MC simulation package for clinical PET applications and hadrontherapy research.
- To enable the modeling and analysis of PET acquisitions in particle therapy scenarios.
Main Methods:
- Utilized the FLUKA Monte Carlo particle transport code with a dedicated PET simulation package.
- Employed the FLUKA Graphical User Interface (GUI) Flair for configuring PET scanner prototypes.
- Implemented scoring routines for analyzing single/coincident events and parent isotopes, supporting Filtered Back-Projection (FBP) and Maximum-Likelihood Expectation Maximization (MLEM) reconstruction.
Main Results:
- FLUKA PET tools include library models of PET scanners and allow user configuration of new prototypes.
- The tools can simulate PET acquisitions in time, reflecting particle therapy scenarios.
- Successful testing across various detectors and scenarios, including conventional PET and in-beam PET applications.
Conclusions:
- The FLUKA PET tools are suitable for simulating PET scanners and acquisitions in research and development.
- These tools support advanced analysis, including event scoring and isotope identification.
- The package is validated for both functional PET and in-beam PET applications in R&D environments.
Related Concept Videos
Preclinical Development: Overview
Overview of Microsoft Excel as a Data Analysis Tool
In Vitro Drug Release Testing: Overview, Development and Validation
Sustainable Development
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Overview of Metabolism
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...

