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Updated: Feb 7, 2026
04:01
Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
Published on: September 15, 2023
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Prophylactic central neck dissection and local recurrence in papillary thyroid microcarcinoma: a meta-analysis
Brazilian Journal of Otorhinolaryngology
|July 19, 2018
Summary
Prophylactic central neck dissection in papillary thyroid microcarcinoma surgery significantly reduces local recurrence rates. This procedure is safe and effective, though further randomized trials are needed due to low-quality evidence.
Area of Science:
- Endocrinology
- Surgical Oncology
- Oncology
Background:
- Papillary thyroid microcarcinoma (PTMC) has a high incidence of lymph node metastasis (up to 40%), primarily in the central neck compartment.
- Preoperative ultrasonography often fails to detect these metastases, leading to debate on routine central neck dissection (CND).
Purpose of the Study:
- To evaluate the efficacy of prophylactic central neck dissection (pCND) in reducing local recurrence rates for PTMC patients undergoing thyroidectomy.
Main Methods:
- A meta-analysis was conducted on studies published between January 1990 and December 2017.
- Literature search of national and international databases for studies comparing thyroidectomy plus pCND versus thyroidectomy alone for PTMC.
Main Results:
- Four studies involving 727 patients (366 with pCND, 361 without) were included.
- The recurrence rate for pCND was 1.91%, significantly lower than thyroidectomy alone (OR=0.24, p=0.0009).
Conclusions:
- Thyroidectomy plus pCND is a safe and effective procedure for PTMC, leading to reduced recurrence rates.
- High-quality evidence is limited due to the non-randomized nature of the included studies, necessitating further randomized trials.
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