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Functional response of the hyperthyroid patients with beta adrenoreceptor blockade to exercise
Physiologie (Bucarest)
|October 1, 1985
Summary
Hyperthyroid patients showed reduced exercise capacity. Propranolol treatment improved their adaptability to exercise, as measured by the adaptability coefficient (AC).
Area of Science:
- Exercise physiology
- Cardiology
- Endocrinology
Background:
- Hyperthyroidism can affect cardiovascular function and exercise tolerance.
- Assessing exercise adaptability is crucial for managing patients with endocrine disorders.
Purpose of the Study:
- To evaluate exercise adaptability in hyperthyroid patients.
- To determine the effect of propranolol on exercise capacity in this population.
Main Methods:
- A submaximal triangular ergometric bicycle test was employed.
- Measurements included heart rate, blood pressure, ECG, CO2 output, O2 consumption (VO2 max), and subjective exertion (Borg scale).
- The adaptability coefficient (AC) was calculated to quantify exercise capacity.
Main Results:
- Hyperthyroid patients exhibited decreased exercise capacity before propranolol treatment.
- Following propranolol administration, a significant increase in exercise capacity was observed.
- The adaptability coefficient (AC) reflected these changes in exercise tolerance.
Conclusions:
- Hyperthyroidism impairs exercise adaptability.
- Propranolol treatment can improve exercise capacity in hyperthyroid patients, suggesting a role in managing their physical well-being.