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Published on: January 12, 2018
Visual and Hearing Impairments After Preterm Birth
Mikko Hirvonen1,2, Riitta Ojala2,3, Päivi Korhonen2,3
1Department of Pediatrics, Central Finland Health Care District, Jyväskylä, Finland; mikko.hirvonen@ksshp.fi.
Insights
Sensory impairments like hearing loss and visual impairment are more common in preterm infants, with risks increasing with earlier birth. Intracranial hemorrhage and convulsions are key risk factors for these neurosensory disabilities.
Area of Science:
- Neonatalogy
- Public Health
- Ophthalmology
- Audiology
Background:
- Preterm birth is a significant risk factor for neurodevelopmental issues.
- Sensory impairments, including hearing loss and visual disturbances, can have long-term impacts on child development.
- Understanding the incidence and risk factors of these impairments is crucial for early intervention.
Purpose of the Study:
- To compare the incidences of sensory impairments across different gestational age groups: very preterm, moderately preterm, late preterm, and term infants.
- To identify and establish risk factors associated with neurosensory disabilities in infants.
Main Methods:
- A national register study analyzing live-born infants in Finland from 1991 to 2008.
- Exclusion of infants with major congenital anomalies, early mortality, or missing data.
- Determination of incidences of hearing loss, visual impairments, and retinopathy of prematurity by gestational age, with risk factor analysis.
Main Results:
- Incidences of sensory impairments decreased significantly with increasing gestational age at birth.
- Intracranial hemorrhage and convulsions were the most prominent risk factors for both hearing loss and visual impairment.
- Very preterm and late preterm births were associated with increased risk of hearing loss.
- Very preterm, moderately preterm, and late preterm births were associated with increased risk of visual impairment.
Conclusions:
- Gestational age at birth is a critical determinant of sensory impairment risk, with lower gestational ages posing higher risks.
- Intracranial hemorrhage and convulsions are significant predictors of sensory disabilities in infants.
- Targeted monitoring and preventative strategies for preterm infants, particularly those experiencing intracranial hemorrhage or convulsions, are warranted.
Objectives:
Our aim was to determine and compare the incidences of sensory impairments among very preterm (VP) (<32 + 0/7 weeks), moderately preterm (MP) (32 + 0/7-33 + 6/7 weeks), late preterm (LP) (34 + 0/7-36 + 6/7 weeks), and term infants (≥37 weeks) and to establish risk factors of neurosensory disabilities.
Methods:
This national register study included all live-born infants in Finland between 1991 and 2008. Infants who died before the age of 1 year, who had any major congenital anomaly, or had missing data were excluded (n = 21 007; 2.0%). A total of 1 018 256 infants were analyzed. Incidences of hearing loss, visual disturbances or blindness, other ophthalmologic disorders, and retinopathy of prematurity were determined for gestational age (GA) groups. Risk factors of hearing loss and visual disturbances or blindness were analyzed.
Results:
The incidences of sensory impairments decreased with advancing GA at birth (P < .001). The most prominent factors associated with increased risks of hearing loss and visual impairment were intracranial hemorrhage and convulsions. VP (odds ratio [OR] 2.34; 95% confidence interval [CI] 1.75-3.14) and LP (OR 1.26; 95% CI 1.04-1.52) births were associated with an increased risk of hearing loss, and VP (OR 1.94; 95% CI 1.55-2.44), MP (OR 1.42; 95% CI 1.11-1.80), and LP (OR 1.31; 95% CI 1.16-1.49) births predicted an increased risk of visual impairment.
Conclusions:
Incidences of sensory impairment decreased with increasing GA at birth. The most prominent risk factors predictive of sensory disabilities were intracranial hemorrhage and convulsions. VP and LP births were associated with an increased risk of hearing loss, and VP, MP, and LP births were associated with an increased risk of visual impairment.
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