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Published on: December 23, 2017
Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion
Mehdi Sharifi-Rad1, Patrick Valere Tsouh Fokou2, Farukh Sharopov3
1Department of Medical Parasitology, Zabol University of Medical Sciences, Zabol 61663335, Iran. mehdi_sharifirad@yahoo.com.
Abstract:
In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.
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