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Updated: Feb 7, 2026

High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo
Published on: November 8, 2018
Ultrasound Elastography can Detect Placental Tissue Abnormalities
Tomoya Hasegawa1, Naoaki Kuji1, Fumiaki Notake2
1Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan.
Ultrasound elastography can assess placental hardness, which correlates with lower fetal weight and birth weight. This technique may serve as an additional marker for intrauterine fetal well-being.
Area of Science:
- Obstetrics and Gynecology
- Medical Imaging
- Fetal Medicine
Background:
- Elastography is an ultrasound technique that measures tissue stiffness.
- Evaluating placental function is crucial for monitoring fetal well-being.
- This study investigated elastography's utility in assessing the placenta and fetus.
Purpose of the Study:
- To examine the utility of ultrasound elastography in evaluating placental characteristics.
- To correlate placental hardness measurements with fetal growth parameters.
- To assess elastography as a potential marker for intrauterine fetal well-being.
Main Methods:
- A prospective cohort study included 111 pregnant women in their third trimester.
- Ultrasound elastography was used to measure placental index (PI) and hardness (HT score).
- 40 placentas underwent pathological examination post-delivery.
Main Results:
- The placental index (PI) was significantly higher in the small for gestational age (SGA) group compared to the normal group.
- PI showed significant negative correlations with estimated fetal weight (EFW) and birth weight z-scores.
- Placental pathological ischemia findings were more prevalent in higher HT score groups.
Conclusions:
- Placental hardness measured by elastography correlates with reduced fetal and birth weight.
- Ultrasound elastography of the placenta may offer an additional method for assessing fetal well-being.
- Elastography shows promise as a non-invasive tool in prenatal diagnostics.
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