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Association Between Cholangiocarcinoma and Proton Pump Inhibitors Use: A Nested Case-Control Study

Yen-Chun Peng1,2, Cheng-Li Lin3,4, Wan-Yun Hsu5

  • 1Division of Gastroenterology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.

Frontiers in Pharmacology
|July 19, 2018
PubMed
Summary

Proton pump inhibitor (PPI) use was associated with increased odds of developing cholangiocarcinoma (CCA), including both intrahepatic and extrahepatic types. Further research is needed to confirm these findings.

Keywords:
case-control studycholangiocarcinomadefined daily doseodds ratiosproton pump inhibitors

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