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Synthesis of High Purity Nonsymmetric Dialkylphosphinic Acid Extractants
Published on: October 19, 2017
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An efficient synthesis of 1,6-anhydro-N-acetylmuramic acid from N-acetylglucosamine
Matthew B Calvert1,2, Christoph Mayer3, Alexander Titz1,2,4
1Chemical Biology of Carbohydrates, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), D-66123 Saarbrücken, Germany.
Beilstein Journal of Organic Chemistry
|July 19, 2018
Abstract:
A novel synthesis of 1,6-anhydro-N-acetylmuramic acid is described, which proceeds in only five steps from the cheap starting material N-acetylglucosamine. This efficient synthesis should enable future studies into the importance of 1,6-anhydromuramic acid in bacterial cell wall recycling processes.
Keywords:
N-acetylmuramic acidanhydrosugarsantibiotic resistancebacterial cell wall recyclingcarbohydrate synthesisMore Related Videos
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