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Iris melanoma presenting as childhood glaucoma

Briana C Gapsis1, Nichelle A Warren1, Matthew J Nutaitis1

  • 1Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, SC, USA.

American Journal of Ophthalmology Case Reports
|July 20, 2018
PubMed

Insights

This study details a rare pediatric iris melanoma case, highlighting early detection and treatment with Iodine-125 plaque brachytherapy. Prompt management is crucial for reducing local progression and metastasis risks in pediatric uveal melanoma.

Area of Science:

  • Ophthalmology
  • Pediatric Oncology
  • Medical Case Study

Background:

  • Iris melanoma is a rare ocular tumor, particularly in pediatric populations.
  • Early diagnosis and management are critical for favorable outcomes.
  • Pediatric uveal melanoma presents unique challenges in treatment and monitoring.

Observation:

  • A 7-year-old female presented with pupillary abnormalities, progressing to iris changes by age 9.
  • At 11, she had elevated intraocular pressure and optic nerve cupping due to a pigmented iris lesion invading the angle.
  • Trans-corneal fine needle aspirate biopsy confirmed malignant iris melanoma.

Findings:

  • The pediatric patient was treated with Iodine-125 plaque brachytherapy for the iris melanoma.
  • Management of associated glaucoma required careful consideration of tumor-specific factors.
  • Early identification and intervention are key to preventing local tumor progression.

Implications:

  • This case underscores the importance of vigilance for rare pediatric ocular tumors.
  • Effective treatment strategies for pediatric iris melanoma require a multidisciplinary approach.
  • Addressing both the tumor and secondary glaucoma is vital for preserving vision and preventing metastasis.
Abstract

Keywords:
GlaucomaIris melanomaPediatric

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