Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Photoluminescence: Applications

Photoluminescence: Applications

Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...

Radiation: Applications

Radiation: Applications

The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...

Applications of Logarithms

Applications of Logarithms

Logarithmic functions are powerful tools for simplifying the mathematical representation of phenomena involving exponential changes. Their ability to convert multiplicative relationships into additive ones is especially valuable in various scientific and engineering contexts. One notable application of logarithms is measuring sound intensity, specifically through the decibel (dB) scale used in acoustics.Sound intensity levels vary over an extensive range, from the faintest audible whisper to...

Applications of Stress

Applications of Stress

Consider a structure made of a boom and a rod designed to support a load. These two components are connected by a pin and stabilized by brackets and pins. The boom and the rod are detached from their supports to assess the different stresses imposed on this structure, and a free-body diagram is drawn. Then, all the forces applied, including the load acting on the structure, are identified. The reaction forces exerted on both the boom and the rod are computed using the equilibrium equations.
The...

Applications of RC Circuits

Applications of RC Circuits

A relaxation oscillator is one of the applications of RC circuits. A neon lamp relaxation oscillator comprises a capacitor, a resistor, a voltage source, and a lamp. The lamp acts like an open circuit, with infinite resistance until the potential difference across the lamp reaches a specific voltage. At that voltage, the lamp acts like a short circuit with zero resistance, and the capacitor discharges through the lamp, thus producing light. Once the capacitor is fully discharged through the...

Bernoulli's Principle: Applications

Bernoulli's Principle: Applications

There are many devices and situations in which fluid flows at a constant height and so can be analyzed using Bernoulli's principle. These devices include, but are not limited to, entrainment devices and fluid flow measuring devices.
Entrainment devices use a high fluid speed to create low pressures and, thus, entrain one fluid into another. Some examples of these devices are given below:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Identification of drug candidates against glioblastoma with machine learning and high-throughput screening of heterogeneous cellular models.

Digital discovery·2026

Same author

Spiro‑Linked Double Tetraphenylethenes: Solid-State Emission and Circularly Polarized Luminescence Imaging.

Angewandte Chemie (International ed. in English)·2026

Same author

Discovery of a Highly Potent and Selective mTOR Inhibitor that Strongly Suppresses Glioblastoma Multiforme Cell Growth.

Journal of medicinal chemistry·2026

Same author

Protein-Directed Nucleation and Stabilization of Ultrasmall Silver Nanoparticles Within BSA Hydrogels.

Gels (Basel, Switzerland)·2026

Same author

Identification of a new selective ligand for targeting neuronal K<sub>V</sub>4.3/KChIP3 over cardiac K<sub>V</sub>4.3/KChIP2 channels.

Biochemical pharmacology·2026

Same author

Leukemia cutis as the first manifestation of acute myeloid leukemia.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026

Search research articles

Related Experiment Video

Updated: Feb 7, 2026

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

Published on: April 28, 2015

Metallofluorescent Nanoparticles for Multimodal Applications.

Antonio Delgado-Gonzalez^1,2, Emilio Garcia-Fernandez¹, Teresa Valero^1,2

¹Department of Medicinal and Organic Chemistry, Faculty of Pharmacy, and Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Campus Cartuja, 18071 Granada, Spain.

|July 20, 2018

Summary

This summary is machine-generated.

Researchers developed dual-function polystyrene particles with fluorescent tags and metals. These particles enable cell fingerprinting via flow cytometry and can act as heterogeneous catalysts, showcasing versatile applications in nanotechnology and chemistry.

More Related Videos

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

Manufacture and Drug Delivery Applications of Silk Nanoparticles

Manufacture and Drug Delivery Applications of Silk Nanoparticles

Published on: October 8, 2016

Related Experiment Videos

Last Updated: Feb 7, 2026

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

Published on: April 28, 2015

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

Manufacture and Drug Delivery Applications of Silk Nanoparticles

Manufacture and Drug Delivery Applications of Silk Nanoparticles

Published on: October 8, 2016

Area of Science:

Materials Science
Nanotechnology
Analytical Chemistry

Background:

Development of multifunctional nanoparticles is crucial for advanced analytical and catalytic applications.
Polystyrene-based particles offer a versatile platform for incorporating diverse functionalities.
Dual-modal properties, such as fluorescence and metal content, enhance particle utility.

Purpose of the Study:

To synthesize and characterize cross-linked polystyrene-based dual-function nanoparticles.
To investigate the dual-band fluorescence emission properties of the synthesized particles.
To explore the application of these particles in cell fingerprinting and as heterogeneous catalysts.

Main Methods:

Synthesis of cross-linked polystyrene-based nanoparticles.
Incorporation of fluorescent tags and metal ions.
Characterization of dual-band fluorescence emission.
Nanofection into living cells for flow cytometry.
In situ reduction of metal ions for catalytic studies.

Main Results:

Successfully synthesized dual-function nano- and microparticles with both fluorescent tags and metals.
Particles exhibited characteristic dual-band fluorescence emission from a single dye.
Hybrid metallofluorescent particles were formed by combining with different metal ions.
Effective nanofection into living cells demonstrated for multimodal flow cytometry.
In situ reduction of metal ions indicated potential as heterogeneous catalysts.

Conclusions:

The synthesized polystyrene-based particles offer a novel platform for dual-functionality.
These particles are suitable for advanced cell analysis techniques like multimodal flow cytometry.
The metallofluorescent particles show promise as heterogeneous catalysts, expanding their application scope.