Epidemiological study on accidental poisonings in children from northeast romania

Nicolai Nistor1, Otilia Elena Frasinariu, Aniela Rugină

  • 1Pediatrics Department, University of Medicine and Pharmacy "Grigore T. Popa" "Saint. Mary" Children Emergency Hospital, Iasi, Romania.

Medicine
|July 20, 2018
PubMed

Insights

Accidental poisonings in children are a significant cause of illness and death. Non-medication substances like household chemicals caused most poisonings, highlighting the need for preventative health measures.

Area of Science:

  • Pediatric Toxicology
  • Public Health
  • Epidemiology

Background:

  • Accidental poisonings represent a critical public health concern, particularly for young children, contributing to significant morbidity and mortality.
  • Understanding the patterns of childhood poisoning is essential for developing effective prevention strategies.

Purpose of the Study:

  • To analyze the epidemiological and etiological characteristics of accidental intoxications in children admitted to a toxicology center.
  • To identify the primary causes and age distribution of poisoning cases to inform public health interventions.

Main Methods:

  • A retrospective observational study was conducted over three years at the Regional Center of Toxicology, Children's Emergency Hospital "St. Mary" Iasi.
  • Data from 480 pediatric patients admitted for accidental intoxication were collected and analyzed using SPSS, with a 95% confidence interval.

Main Results:

  • The majority of cases (24.3%) occurred in children aged 1-2 years.
  • Non-medication poisonings (67%) were most common, including household chemicals, carbon monoxide, and insecticides. Medication poisonings accounted for 33%, with anticonvulsants, NSAIDs, and paracetamol being frequent culprits.
  • The overall mortality rate was 0.62%, exclusively from non-medication intoxications.

Conclusions:

  • Accidental intoxications in children are a preventable cause of severe health outcomes.
  • Public health systems must prioritize understanding and addressing the epidemiological trends of childhood poisoning to reduce incidence and severity through targeted measures.

Related Concept Videos

Study Designs in Epidemiology01:20

Study Designs in Epidemiology

Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
1.0K
Confounding in Epidemiological Studies01:27

Confounding in Epidemiological Studies

Confounding in statistical epidemiology represents a pivotal challenge, referring to the distortion in the perceived relationship between an exposure and an outcome due to the presence of a third variable, known as a confounder. This variable is associated with both the exposure and the outcome but is not a direct link in their causal chain. Its presence can lead to erroneous interpretations of the exposure's effect, either exaggerating or underestimating the true association. This...
846
Bias in Epidemiological Studies01:29

Bias in Epidemiological Studies

Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:  
1.4K
Enhanced Elimination of Poison01:26

Enhanced Elimination of Poison

Poison can be effectively removed from the gastrointestinal (GI) tract through various decontamination procedures.
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
914
Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
1.3K
Introduction to Epidemiology01:26

Introduction to Epidemiology

Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
1.9K