Epidemiological study on accidental poisonings in children from northeast romania
Nicolai Nistor1, Otilia Elena Frasinariu, Aniela Rugină
1Pediatrics Department, University of Medicine and Pharmacy "Grigore T. Popa" "Saint. Mary" Children Emergency Hospital, Iasi, Romania.
Insights
Accidental poisonings in children are a significant cause of illness and death. Non-medication substances like household chemicals caused most poisonings, highlighting the need for preventative health measures.
Area of Science:
- Pediatric Toxicology
- Public Health
- Epidemiology
Background:
- Accidental poisonings represent a critical public health concern, particularly for young children, contributing to significant morbidity and mortality.
- Understanding the patterns of childhood poisoning is essential for developing effective prevention strategies.
Purpose of the Study:
- To analyze the epidemiological and etiological characteristics of accidental intoxications in children admitted to a toxicology center.
- To identify the primary causes and age distribution of poisoning cases to inform public health interventions.
Main Methods:
- A retrospective observational study was conducted over three years at the Regional Center of Toxicology, Children's Emergency Hospital "St. Mary" Iasi.
- Data from 480 pediatric patients admitted for accidental intoxication were collected and analyzed using SPSS, with a 95% confidence interval.
Main Results:
- The majority of cases (24.3%) occurred in children aged 1-2 years.
- Non-medication poisonings (67%) were most common, including household chemicals, carbon monoxide, and insecticides. Medication poisonings accounted for 33%, with anticonvulsants, NSAIDs, and paracetamol being frequent culprits.
- The overall mortality rate was 0.62%, exclusively from non-medication intoxications.
Conclusions:
- Accidental intoxications in children are a preventable cause of severe health outcomes.
- Public health systems must prioritize understanding and addressing the epidemiological trends of childhood poisoning to reduce incidence and severity through targeted measures.
Abstract:
Accidental poisonongs are an important cause of morbidity and even mortality, especially in young children.We performed a retrospective observational study on a group of children admitted at the Regional Center of Toxicology at the Children's Emergency Hospital "St. Mary" Iasi with accidental intoxication within a period of 3 years. Data were collected from patients' files and processed with a SPPS 18.0 database and a 95% confidence interval.During this period, 480 children were admitted with accidental intoxication. Most of them were in the age group of 1 to 2 years (120 cases-24.3%). The etiology of these intoxications was dominated by nonmedication (67%), the most frequent being household chemicals, carbon monoxide, and insecticides. Accidental drug intoxication accounted for 33% of the cases, the main drugs involved being anticonvulsants, nonsteroidal anti-inflammatory drugs, and paracetamol. The mortality caused by accidental poisoning was 0.62%, all deaths owing to nonmedication intoxication.Identifying the epidemiological and evolutionary aspects of accidental intoxications must be a major objective for the health system, given that this pathology can be at least partially avoided and its incidence and severity may be reduced using appropriate measures.
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