Related Experiment Video
Updated: Feb 7, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Low-dose vitamin A therapy on T lymphocyte function in neonatal pneumonia
1Department of Neonatology, The Children & Women's Healthcare of Laiwu City, Laiwu 271199, P.R. China. 76304338@qq.com.
Objective:
We aimed at studying the effect of adjuvant therapy with low-dose vitamin A on the function of T lymphocytes in neonatal pneumonia.
Patients And Methods:
We recruited 60 cases of neonatal pneumonia which were randomly divided in two equal groups. The control group was treated with conventional anti-inflammatory therapy and aerosol inhalation. The experimental group received oral vitamin A soft capsules for 7 days.
Results:
Pre-treatment levels vitamin A level and vitamin A deficiency disorders (VADD) percentage revealed no differences between the two groups. The treatment course for the experimental group was shorter than the control group. Serum IgM, IgG, and glutathione peroxidase (GSH-Px) levels were increased, whereas the levels of malondialdehyde were decreased in the experimental group after treatment. The control group showed no changes in these factors. After treatment, both groups showed increased percentages of CD4+ and CD8+ T cells, but the experimental group showed a larger increase.
Conclusions:
Neonatal pneumonia is often accompanied by a low level of vitamin A, and adjuvant therapy can shorten its disease course, improve IgM and IgG levels, and improve anti-oxidative and cellar immune function.
More Related Videos
09:17A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii
Published on: January 2, 2017
09:31Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
Published on: January 27, 2023
Related Concept Videos
Vitamins
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia II: Pathophysiology
Dose Size and Dosing Frequency: Determination Methods
Determination of Multiple Dosing Parameters: Loading and Maintenance Doses
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include: