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Molecular compounds or covalent compounds result when atoms share electrons to form covalent bonds. Since there is no electron transfer, molecular compounds do not contain ions; instead, they consist of discrete, neutral molecules. 
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In most main group element compounds, the valence electrons of the isolated atoms combine to form chemical bonds that satisfy the octet rule. For instance, the four valence electrons of carbon overlap with electrons from four hydrogen atoms to form CH4. The one valence electron leaves sodium and adds to the seven valence electrons of chlorine to form the ionic formula unit NaCl (Figure 1a). Transition metals do not normally bond in this fashion. They primarily form coordinate covalent bonds, a...
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An element composed of atoms that readily lose electrons (a metal) can react with an element composed of atoms that readily gain electrons (a nonmetal) to produce ions through complete electron transfer. The compound formed by this transfer is stabilized by the electrostatic attractions (ionic bonds) between the oppositely charged ions.
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During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United States Adopted Name (USAN)—a generic, nonproprietary designation. Upon being listed in the United States Pharmacopeia, this nonproprietary name becomes the drug's official name. Additionally, the manufacturer assigns a proprietary name or trademark, which serves as the brand name under which the drug is marketed. It is worth noting that...
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The IUPAC naming system for alkenes replaces -an- with -en- in the corresponding parent alkanes. Accordingly, a simple alkene replaces the -ane suffix of the alkane with -ene.
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In the late 19th-century, the number of new chemical compounds discovered increased tremendously. Hence, the necessity arose to develop a naming system for the systematic nomenclature of these newly discovered compounds. IUPAC (International Union for Pure and Applied Chemistry), established in 1919, sets rules for the nomenclature.
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Rethinking Pharmacological Nomenclature.

Roland Seifert1

  • 1Institute of Pharmacology, Hannover Medical School, Carl-Neuberg-Straße 1, D-30625 Hannover, Germany.

Trends in Pharmacological Sciences
|July 21, 2018
PubMed
Summary

Rethinking pharmacological terms is crucial as drug targets advance. A mechanism-based nomenclature, like for disease-modifying antirheumatic drugs (DMARDs), enhances drug safety and therapy quality.

Keywords:
DMARDNSAIDantihistaminebeta blockercalcium antagonistpharmacological nomenclature

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Area of Science:

  • Pharmacology
  • Drug Discovery
  • Medical Education

Background:

  • Traditional pharmacological nomenclature, established over a century ago, persists in current medical and scientific literature.
  • Advancements in identifying molecular drug targets necessitate a re-evaluation of existing drug class names.
  • Established drug classes include antihistamines, beta blockers, calcium antagonists, disease-modifying antirheumatic drugs (DMARDs), and non-steroidal anti-inflammatory drugs (NSAIDs).

Purpose of the Study:

  • To propose a shift towards mechanism-based nomenclature for pharmacological terms.
  • To stimulate community discussion on optimizing drug naming conventions.
  • To highlight the benefits of mechanism-oriented drug classification.

Main Methods:

  • This opinion article reviews existing pharmacological terms and proposes a new naming strategy.
  • It advocates for a nomenclature system based on drug mechanisms of action.
  • Suggests the development of abbreviations for new drug classes.

Main Results:

  • A mechanism-based nomenclature offers significant advantages over traditional naming conventions.
  • This approach provides clearer insights into both therapeutic effects and potential adverse drug reactions.
  • Proposed abbreviations for drug classes aim for greater practicality.

Conclusions:

  • Adopting a parsimonious, practical, and mechanism-oriented pharmacological nomenclature is essential.
  • This revised system promises to improve the overall quality and safety of drug therapy.
  • Enhanced understanding of drug action through nomenclature can lead to better patient outcomes.