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Elastic Staining on Paraffin-embedded Slides of pT3N0M0 Gastric Cancer Tissue
Published on: May 1, 2019
Immunotherapy in Advanced Gastric Cancer: An Overview of the Emerging Strategies
Helena Magalhães1, Mário Fontes-Sousa1, Manuela Machado1
1Medical Oncology Department, Portuguese Institute of Oncology of Porto (IPO Porto), Porto, Portugal.
Abstract:
Gastric cancer (GC) remains a public health problem, being the fifth most common cancer worldwide. In the western countries, the majority of patients present with advanced disease. Additionally, 65 to 75% of patients treated with curative intent will relapse and develop systemic disease. In metastatic disease, systemic treatment still represents the state of the art, with less than a year of median overall survival. The new molecular classification of GC was published in 2014, identifying four distinct major subtypes of gastric cancer, and has encouraged the investigation of new and more personalized treatment strategies. This paper will review the current evidence of immunotherapy in advanced gastric cancer.
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