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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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Androgenic modulation of AR-Vs

Ana Caroline Hillebrand1, Lolita Schneider Pizzolato1, Gisele Branchini2

  • 1Laboratory of Molecular Endocrine and Tumoral Biology, Department of Physiology, Institute of Basic Sciences of Health, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, 90050-170, Brazil.

Endocrine
|July 21, 2018
PubMed
Summary

Androgen receptor variants (AR-Vs) expression dynamically changes with androgen levels in prostate cancer cells. Understanding these AR-V dynamics is crucial for developing new prostate cancer therapies.

Keywords:
Androgen receptorAndrogen receptor isoformsAndrogen receptor variantsAndrogenic modulationProstate cancerSteroids

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