Related Experiment Video
Updated: Feb 7, 2026

Extended Live Imaging of Female Drosophila melanogaster Germline Stem Cell Niches
Published on: December 20, 2024
Mitochondrial Redox Sensor for Drosophila Female Germline Stem Cells
Kiran Suhas Nilangekar1, Bhupendra V Shravage2
1Developmental Biology Group, MACS-Agharkar Research Institute, Pune, India.
Abstract:
Mitochondrial reactive oxygen species (mROS), a major source of ROS within cells, functions as an important signaling molecule and has the ability to damage cellular macromolecules including DNA and proteins. Monitoring mROS levels is therefore essential to understand cell-cell communication and programmed cell death in all types of cell including stem cells. Here, we describe generation and characterization of a redox sensor for mROS that is specifically expressed in the germline stem cells (GSCs) in Drosophila. This redox sensor can be used to monitor the production of mROS and mitophagy in the GSCs during oogenesis.
Related Concept Videos
Balancing Redox Equations
Redox Reactions
Redox Reactions
Animal Mitochondrial Genetics
Adult Stem Cells
Embryonic Stem Cells

