[The treatment of gastroenteropancreatic neuroendocrine tumors]

Gastroenteropancreatic neuroendocrine tumors have been increasing in frequency over the past decades. The goal of this paper is to provide a concise overview of various treatment options based mainly on consensus guidelines. The only curative therapy for these tumors is timely surgical intervention including endoscopic removal of early stage neuroendocrine tumors. Since at initial diagnosis about half of these patients present with advanced disease, systemic drug and non-drug treatments are discussed in details. Therapeutic approaches of advanced stages include surgical, medical, interventional radiological and nuclear medicine strategies. The aims of treatment are to provide an appropriate antisecretory and antiproliferative effect. Optimization of diverse treatment strategies is best achieved by multidisciplinary approaches.