Detection of a transient FeV(O)(OH) species involved in olefin oxidation by a bio-inspired non-haem iron catalyst
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Updated: Feb 7, 2026

Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection
Published on: February 16, 2020
Shuangning Xu1, Jedidiah J Veach2, Williamson N Oloo1
1Department of Chemistry and Center for Metals in Biocatalysis, University of Minnesota, Minneapolis, Minnesota 55455, USA. larryque@umn.edu.
Abstract:
The Fe(TPA) (TPA = tris(pyridyl-2-methyl)amine) class of non-haem Fe catalysts is proposed to carry out selective hydrocarbon oxidations through the generation of high-valent iron species. Using ambient mass spectrometry, we obtain direct evidence for the formation of an FeV(O)(OH) species under catalytic conditions. In addition, 18O-labelling suggests that this FeV(O)(OH) species serves as the active oxidant in hydrocarbon oxidation catalysis.
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