[Cyc1AMP levels and effect of calcium regulating hormones]

Effects of calcitonin and parathyroid hormone on the functional activity of contractile cardiomyocytes were studied against the background of theophylline blockade of phosphodiesterase, as well as effects of calcitonin on activity of contractile and pace-maker cardiomyocytes and of the parathyroid hormone on activity of contractile myocytes in conditions of adrenaline stimulation of adenyl cyclase. The data obtained show a difference in effects of calcitonin and parathyroid hormone upon the myocardium under conditions of an increased intracellular level of cAMP induced with theophylline and adrenaline.